Dihydrotachysterol

  • Name: Dihydrotachysterol
  • CAS: 67-96-9
  • Purity: 99%
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1.What is the Dihydrotachysterol ?

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ChEBI: A hydroxy seco-steroid that is 9,10-secoergosta-5,7,22-triene substituted by a hydroxy group at position 3. A synthetic analogue of vitamin D that acts a bone density conservation agent.

Dihydrotachysterol is a synthetic analog of vitamin D. It is considered as a reduction product of vitamin D2 (ergocalciferol). It stimulates bone mineralization as well as calcium and phosphorus absorption in intestine. Dihydrotachysterol has been used for the treatment of hypoparathyroidism, osteomalacia, osteoporosis, low calcium level, and kidney osteodystrophy. Though dihydrotachysterol is more expensive, dihydrotychysterol therapy is preferred as it has a more rapid onset of action (1-7 d) and a shorter time for dissipation of effect in the event of toxicity (2-3 weeks) than vitamin D2.

2.What is the CAS number for Dihydrotachysterol ?

The CAS number of Dihydrotachysterol is 67-96-9.

3.What are another words for Dihydrotachysterol ?

Synonyms?for?Dihydrotachysterol 67-96-9:9,10-Secoergosta-5,7,22-trien-3-ol,(3b,5E,7E,10a,22E)- (9CI);Tachysterol,dihydro- (7CI,8CI);Tachysterol2, dihydro- (6CI);24-Methyl-9,10-secocholesta-5,7,22-trien-3b-ol;9,10-Secoergosta-5,7,22-trien-3b-ol;A.T. 10;A.T. 10 (steroid);Anti-tetany substance 10;Antitanil;Calcamine;DHT2;Dichystrolum;Dihydral;

4.What is Dihydrotachysterol (67-96-9) used for?

Calcium regulator. Preparation by reduction of Tachysterol. It is widely used for hypocalcemic hypoparathyroidism following surgical removal of parathyroids.

InChI:InChI=1/C28H46O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-22,25-27,29H,7-8,11,14-18H2,1-6H3/b10-9+,23-12+,24-13+

Relevant articles related to Dihydrotachysterol:

Article

Source

A Convergent Approach to the Dihydrotachysterol Diene System. Application to the Synthesis of Dihydrotachysterol2 (DHT2), 25-Hydroxydihydrotachysterol2 (25-OH-DHT2), 10(R),19-dihydro-(5E)-3-epivitamin D2, and 25-Hydroxy-10(R),19-dihydro-(5E)-3-epivitamin D2

Maestro, Miguel A.,Castedo, Luis,Mourino, Antonio

, p. 5208 - 5213 (2007/10/02)

Hydrotitanation-Protonation of Vitamin D2 and Its Analogues: An Efficient Method for the Preparation of 10,19-Dihydrovitamins D2 Including Dihydrotachysterol2

Cota, J. G.,Meilan, M. C.,Mourino, A.,Castedo, L.

, p. 6094 - 6099 (2007/10/02)

Administration of biologically active vitamin D3 and vitamin D2 materials

-

, (2008/06/13)

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