2-amino-6-hydroxy-5-methyl-1H-pyrimidin-4-one

  • Name: 2-amino-6-hydroxy-5-methyl-1H-pyrimidin-4-one
  • CAS: 6627-65-2
  • Purity: 99%
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Details

Cost-effective and customizable 2-amino-6-hydroxy-5-methyl-1H-pyrimidin-4-one 6627-65-2 supplier

  • Molecular Formula: C5H7N3O2
  • Molecular Weight: 141.129
  • Vapor Pressure: 2.78E-08mmHg at 25°C 
  • Boiling Point: 478.1°Cat760mmHg 
  • PKA: 7.92±0.10(Predicted) 
  • Flash Point: 242.9°C 
  • PSA： 92.00000 
  • Density: 1.67g/cm3 
  • LogP: -0.05270 

2-amino-6-hydroxy-5-methyl-1H-pyrimidin-4-one(Cas 6627-65-2) Usage

General Description

2-amino-6-hydroxy-5-methyl-1H-pyrimidin-4-one, also known as methyluracil, is a heterocyclic compound with the molecular formula C5H6N2O2. It is a derivative of uracil, an important component of nucleic acids. Methyluracil has been identified as a potent antioxidant and has potential applications in pharmaceuticals and as a supplement in cosmetic products. It has been studied for its potential role in the treatment of inflammatory conditions, as well as for its potential to promote wound healing. Additionally, it has been investigated for its potential to protect against radiation-induced damage. Methyluracil is an important compound with diverse potential applications across various fields.

InChI:InChI=1/C14H9NO2S2/c16-13-12(8-10-6-7-18-9-10)19-14(17)15(13)11-4-2-1-3-5-11/h1-9H/b12-8-

6627-65-2 Relevant articles

5-substituted 2-amino-4,6-dihydroxypyrimidines and 2-amino-4, 6-dichloropyrimidines: Synthesis and inhibitory effects on immune-activated nitric oxide production

Jansa, Petr,Hol, Antonn,Dransk, Martin,Kolman, Viktor,Janeba, Zlatko,Kosteck, Petra,Kmonkov, Eva,Zdek, Zdenk

, p. 4482 - 4490 (2015/04/22)

A series of 5-substituted 2-amino-4,6-di...

5-Substituted 2-amino-4, 6-dihydroxypyrimidines and 2-amino-4, 6-dichloropyrimidines: Synthesis and inhibitory effects on immune-activated nitric oxide production

Jansa, Petr,Holy, Antonín,Dra?ínsky, Martin,Kolman, Viktor,Janeba, Zlatko,Kostecká, Petra,Kmoní?ková, Eva,Zídek, Zdeněk

, p. 4482 - 4490 (2015/04/14)

A series of 5-substituted 2-amino-4, 6-d...

PYRIMIDINE COMPOUNDS INHIBITING THE FORMATION OF NITRIC OXIDE AND PROSTAGLANDIN E2, METHOD OF PRODUCTION THEREOF AND USE THEREOF

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Page/Page column 32-33, (2012/09/21)

The invention provides pyrimidine compou...

Pyrimidines and uses thereof

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, (2008/06/13)

The invention relates to pyrimidines and...

6627-65-2 Process route

guanidine hydrochloride
50-01-1

guanidine hydrochloride

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

2-amino-4,6-dihydroxy-5-methylpyrimidine
6627-65-2

2-amino-4,6-dihydroxy-5-methylpyrimidine

Conditions
Conditions Yield
guanidine hydrochloride; Diethyl methylmalonate; With sodium; In ethanol; at 20 ℃; for 4h; Inert atmosphere;
In ethanol; for 1h; Inert atmosphere; Reflux;
91%
With sodium; In ethanol; Inert atmosphere;
91%
2-amino-4,6-dihydroxy-5-methylpyrimidine
6627-65-2

2-amino-4,6-dihydroxy-5-methylpyrimidine

Conditions
Conditions Yield
91%
90%

6627-65-2 Upstream products

  • 50-01-1
    50-01-1

    guanidine hydrochloride

  • 609-08-5
    609-08-5

    Diethyl methylmalonate

6627-65-2 Downstream products

  • 7153-13-1
    7153-13-1

    4,6-dichloro-5-methylpyrimidin-2-amine

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